Single cell transcriptome in aneuploidies reveals mechanisms of gene dosage imbalance
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چکیده
منابع مشابه
I-13: Transcriptome Dynamics of Human and Mouse Preimplantation Embryos Revealed by Single Cell RNA-Sequencing
Background: Mammalian preimplantation development is a complex process involving dramatic changes in the transcriptional architecture. However, it is still unclear about the crucial transcriptional network and key hub genes that regulate the proceeding of preimplantation embryos. Materials and Methods: Through single-cell RNAsequencing (RNA-seq) of both human and mouse preimplantation embryos, ...
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Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland. Institute of Genetics and Genomics in Geneva, University of Geneva, Geneva, Switzerland. Swiss Institute of Bioinformatics, Geneva, Switzerland. Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK. Department of Genetics, Stanford University, Stanford, California, USA. Department of Twi...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2019
ISSN: 2041-1723
DOI: 10.1038/s41467-019-12273-8